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Listed 24Updated Sep 12, 2026

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  1. Open InterpreterNatural-language computer use that runs code locally.agpl-3.0 · linux, macos, +161k
  2. LlamaIndexThe MIT Python framework for building document ingestion and RAG pipelines.mit · linux, macos, +152k
  3. pytorch-lightningPretrain, finetune ANY AI model of ANY size on 1 or 10,000+ GPUs with zero code changes.apache-2.0 · linux31.3k
  4. ChromaDeveloper-friendly embedding database for local RAG prototypes.apache-2.0 · linux, macos, +223k
  5. txtaiAll-in-one Python framework for embeddings, vector search, and RAG workflows.apache-2.0 · linux, macos, +113k
  6. R2RSoTA production-ready AI retrieval system. Agentic Retrieval-Augmented Generation (RAG) with a RESTful API.mit · linux8k
  7. autoscraperA Smart, Automatic, Fast and Lightweight Web Scraper for Pythonmit · linux8k
  8. fastrtcThe python library for real-time communicationmit · linux4.6k
  9. gptmeMIT terminal agent toolkit with code, shell, and web tools — local-model friendly.mit · linux, macos, +14k
  10. Amazing-Python-Scripts🚀 Curated collection of Amazing Python scripts from Basics to Advance with automation task scripts.mit · linux3.7k
  11. leptonaiA Pythonic framework to simplify AI service buildingapache-2.0 · linux2.8k
  12. mirascopeThe LLM Anti-Frameworkmit · linux1.5k
  13. MemeMeow智能管理表情包mit · linux1.3k
  14. fairseq2FAIR Sequence Modeling Toolkit 2mit · linux1.1k
  15. AgentForgeExtensible AGI Frameworkgpl-3.0 · linux848
  16. phillipThe SSBM "Phillip" AI.gpl-3.0 · linux591
  17. pyswipPySwip is a Python-Prolog interface that enables querying SWI-Prolog in your Python programs.mit · linux548
  18. DI-sheep羊了个羊 + 深度强化学习（Deep Reinforcement Learning + 3 Tiles Game)apache-2.0 · linux519
  19. sraiSpatial Representations for Artificial Intelligence - a Python library toolkit for geospatial machine learning focused on creating embeddings for downstream tasksapache-2.0 · linux390
  20. gradsflow-automlAn open-source AutoML Library based on PyTorchapache-2.0 · linux306
  21. doppel-botTrain a language model to answer Slack messages as you.mit · linux267
  22. AI-Youtube-Shorts-GeneratorInfinite content, zero manual editing. A fully automated 'faceless' video factory that turns trending topics into engaging YouTube Shorts using Gemini AI, Edge-TTS, and dynamic FFmpeg editingmit · linux219
  23. clipspyPython CFFI bindings for the 'C' Language Integrated Production System CLIPSbsd-3-clause · linux203
  24. RamanSPyRamanSPy: An open-source Python package for integrative Raman spectroscopy data analysisbsd-3-clause · linux191